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Mortensen, L. J., Oberdorster, G., Pentland, A. P. & DeLouise, L. A. In vivo skin penetration of quantum dot nanopartiles in the murine model: The effect of UVR.
In a murine model, the prophylactic administration of this Evader™ DsiRNA was effective at partially inhibiting viral replication of hMPV (13 × 103 vs. 29 × 103 PFU/g of lung; p < 0.01), which was not the case for the control, a mismatched DsiRNA.
In our murine model, the concentrations of 32 and 70 mg/kg resulted in significant reductions of the number of bacilli and the pathology in the lung.
In this murine model the duration of the WHO MDR TB treatment could be reduced to 12 months instead of the recommended 18 24 months.
In a murine model, the cytokine IL-1 was shown to induce body weight loss [122].
Next, we decided to evaluate in this murine model the antitumor activity of the combined treatment.
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In both murine models, the primary autoantigen is the protein used to induce the disease.
Yet clinically, and in murine models, the Nav1.5 blocker flecainide reduces ventricular arrhythmogenicity in CPVT.
Thus the murine model reproduces the multiorgan manifestions of the human disease.
This study demonstrates the utility of the murine model for the exploration of pathophysiological mechanisms underlying chronic brucellosis.
To obtain transcriptome information from bacteria colonizing the murine GI tract, we initiated the murine model utilizing the P. aeruginosa PAK strain.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com