Sentence examples for murine model allowed from inspiring English sources

This murine model allowed us to test the hypothesis that inhibition of Ihh signaling decreases cartilage degeneration.

We developed for the first time a murine model allowing for the growth of both MM cell lines and primary cells in multifocal sites, thus mimicking the disease seen in patients.

Murine models allow the application of a broad range of immunological tools as well as gene deletion in vivo.

Furthermore, targeted XIAP knockdown and treatment with a MNK inhibitor decreased tumor cell migration in a dorsal skin fold window chamber murine model that allowed for intravital imaging of local tumor growth and migration.

Taken together, these results demonstrate how the murine model has allowed us to finely dissect two classes of events affecting GAS sociomicrobiology: those related to reversible transcriptional adaptation and those irreversibly caused by the covS mutation in AP bacteria.

These results suggest the potential of the inoculation of genetically engineered FMDV RNA for virulence and protection assays in the murine model and allow to explore the suitability of RNA-based FMDV vaccination in natural host animals.

Three of these, designated as osteoarthritis in Table  2, are scoring systems for human idiopathic arthritis and were transferred to the murine model to allow for comparisons of the model with the human disease.

The use of a xenograft model allowed the differential effects of DMXAA on stroma (murine origin) to be distinguished from its effects on the cancer cells (human origin).

Murine models have allowed further exploration of the role of chemotherapy on the immune system.

However, recent advances include the development of humanized murine models, which allow better vaginal and rectal HIV efficacy-challenge studies.

These efforts have been impeded by the lack of a survivable murine model that reliably allows investigation of the pathogenesis of pleural organization and remodeling.