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The murine mast cell line IC2 was engineered to express murine Kit on the cell surface and was demonstrated to proliferate in the presence of SCF.
IgE/antigen activation of bone marrow-derived mast cells or a murine mast cell line (MC/9) significantly enhanced IL-33.
Recently, Valadi and colleagues reported that vesicles released from human and murine mast cell lines contain over 1200 mRNA and approximately 121 miRNA molecules [20].
Similar vesicles released from human and murine mast cell lines were shown to contain miRNAs [ 8].
The tryptase mMCP6 (murine mast cell protease 6) also contributes potently to neutrophil chemotaxis [ 11].
Furthermore, murine mast cell development is impaired, because of weakened c-Kit signalling [ 115].
Similar(48)
Serotonin is found in murine mast cells and platelets [26], [27] which are both present in the mouse trachea.
Furthermore, STAT4 was required for MCP-1 expression in murine mast cells in response to IFNβ [22].
IL-13 has high similarity with IL-4, which can increase FcγRIII expression on murine mast cells [ 28].
Cystatin F colocalised with cathepsin C in murine mast cells and with the cathepsin C substrate granzyme A in human CD8 T cells.
Moreover, the monomeric cystatin F in dense lysosomal vesicles and those harbouring cathepsin C in murine mast cells appeared to be processed to the truncated active form.
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