Sentence examples for murine intestinal cells from inspiring English sources

These data were derived from measuring DNAm in normal tissue, specifically in human whole-blood tissue (13, 14), as well as in murine intestinal cells (12).

However, the observation that murine intestinal cells secrete the gut-derived incretin hormone glucagon-like peptide-1 (GLP-1) in a Tgr5-dependent manner following in vitro stimulation with the bile acids lithocholic acid and deoxycholic acid revealed a role for TGR5 in glucose homeostasis [ 41, 42].

Recent work on MEX3A in murine intestinal cell culture showed that the master intestinal differentiation factor Cdx2, one of the vertebrate homologs of pal-1, is a target of MEX3A translational inhibition, and furthermore, MEX3A overexpression increased levels of intestinal stem cell markers such as Bmi1 and Lgr5 (Pereira et al., 2013).

CMT-93 murine intestinal epithelial cells, human embryonic kidney 293 (HEK293) cells, and RAW264.7 macrophage cells were maintained in DMEM with 10% FBS (GIBCO-BRL).

Moreover, loss of TLR-4 in murine intestinal epithelial cells has been shown to lead to goblet cell differentiation, probably via suppression of Notch signalling in stem cells 36.

DOI: http://dx.doi.org/10.7554/eLife.06505.005 We next transfected CMT93 cells, a murine intestinal epithelial cell line, with a variety of siRNAs and expression plasmids to evaluate their effects in a bactericidal assay.

Moreover, Apc deletion within the murine intestinal stem cells (ISCs) results in rapid adenoma formation suggesting they can act as cells of origin in CRC (Barker et al, 2009).

Lineage tracing studies using transgenic mouse models have provided significant insight into the dynamics of murine intestinal stem cells, but the significance of these findings for the human intestine has remained in question.

Murine intestinal epithelial cell type Mode-K cells were cultured as previously described by Homaidan et al. (2003) [ 25].

Schneeberger and colleagues demonstrated that organoid cultures of murine intestinal stem cells might serve a useful tool to test future therapies for MVID [19].

Lipid content of isolated murine intestinal epithelial cells (IEC) was analysed by tandem mass spectrometry.