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TRIM28 restricts MLV LTR-driven transcription in murine embryonic cells [12].
To further study the roles of mitochondria in RIBE, in this study, murine embryonic cells lacking cytochrome c (Cyt c) were used as a genetic model.
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Wnt11 promotes cardiac differentiation via the non-canonical pathway in Xenopus [12] and murine embryonic cell lines [19].
C3H cells (C3H10T1/2), a murine embryonic cell line, rarely undergo spontaneous transformation, and are one of the few standard test systems for studying potential carcinogenic agents in animals or humans [ 5].
In this study, we describe a novel in vitro cell culture system for derivation of urothelial cells from murine embryonic stem cells (ESCs) following cultivation on collagen matrices in the presence all trans retinoic acid (RA).
Data from studies with murine embryonic stem cells indicate that these cells efficiently repair DNA damage [ 12- 14], and that repair in embryonic stem cells may even be superior to that in differentiated embryoid bodies or embryonic fibroblasts [ 13].
Murine embryonic stem cells (mESCs) are pluripotent cells that usually proliferate fast and have a high amount of p53.
In order to determine a non-cytotoxic concentration range, cytotoxicity data were obtained for all compounds from HEK293 cells and from murine embryonic stem cells.
Surprisingly, besides mouse fibrosarcoma cells and tumor biopsy from a mouse model of fibrosarcoma, we were also able to detect Mm Xrra1 expression in pluripotent cells such as murine embryonic stem cells R1 (Fig. 4, Table 5).
Murine embryonic stem cells (D3) or D3 derived cells engineered to express EGFP under control of the α-myosin heavy chain promoter (were expanded on MEF feeders (7.5×104 cells per cm2).
Activation of Oct4 gene was achieved with a TALE-VP16 activator in murine embryonic stem cells and derived neural stem cells [ 82].
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