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While these murine data are encouraging, it remains unclear whether AdAg85A will be effective in guinea pig models.
These murine data are also in line with the effect of CRF agonists and antagonists on human hair follicle elongation [5].
In the case of mast cells, only murine data are available, and we presented miRNAs which were significantly upregulated during MC differentiation or could be activated by Fc ɛRI crosslinking in the case of MCs in Table 2. MiR-223 is significantly downregulated during MC differentiation.
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Human data were not available for the numbers of hematogenous metastases sustained by syngeneic hosts, injected with cells from the same tumor and assessed at the same time in the natural history of the disease; but murine data were [ 18, 21, 26].
Murine molecular data are directly endorsed by many epidemiological studies in humans that link extrinsic and intrinsic inflammatory pathways with an increased risk of cancer [ 16].
The radiation-absorbed dose estimated from murine distribution data is highest in the lung but similar in magnitude to most other 11C-labeled PET tracers [22].
The murine microscopy data was analyzed by densitometry (Matlab R2009b, Mathworks Co).
The murine xenograft data were further analysed using pattern recognition software (Genespring GX; Agilent Technologies, Santa Clara, CA, USA).
To demonstrate the prediction values, a subset of murine nutrigenomics data were used (50 transcriptomics and 10 lipidomics variables).
It is important to note that a comparison with murine rAML data is difficult as neither study distinguishes between tAML patients who received radiation therapy alone, chemotherapy alone or a combination of both.
The tight link between the molecular pattern and the disease stage was previously described in murine autoimmune arthritis but no data are available on human RA [ 9].
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