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In human and murine cells, including non-immune cells, the expression of Perforin-2 can be induced by interferons or intracellular bacteria (Fields et al., 2013; McCormack et al., 2013b).
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As shown in Figure 3A, FGF-iPSCc display a gene expression pattern characteristic of murine ES cells, including the inner cell mass markers Rex1, Nanog, Oct4, Sox2, Sall4, Gdf3 and Eras.
Co-culturing of ESCs with murine stromal cells (including PA6 cell line) rapidly generates dopaminergic neurons from ESCs by an unexplained mechanism termed stromal cell-derived inducing activity (SDIA; [ 28, 29]).
However, in 2001, it was suggested independently by 2 groups that monomeric IgE in the absence of antigen can have multiple effects in murine mast cells, including differentiation, proliferation, survival, and mediator and cytokine generation.
We first performed a gene set enrichment analysis (GSEA) comparing the genes bound by different combinations of the three factors with microarray expression data obtained from differentiating murine haematopoietic cells, including HSCs (Chambers et al, 2007; Figure 3D; Supplementary Figure 3A).
We studied the effects of over-expression of Nur77 on the apoptosis of murine peripheral T cells, including thymic-derived Foxp3+ regulatory (Treg) cells.
The C7a complex was cytotoxic in murine and human tumor cells, including cisplatin-resistant lineages.
OSM activates JAK2 and STAT3 upon binding to its receptor in many cells including murine, rat, and human osteoblastic cells and osteosarcoma cell lines [ 21, 22].
Here we show that TOX3 is specifically expressed in the estrogen receptor alpha positive (ER+) subset of murine mammary luminal epithelial cells, including a recently identified progenitor cell subset.
Classically, endogenous MLVs are categorised on the basis of their envelope gene sequence and their cognate receptor polymorphism into ecotropic (replicating only in murine cells), xenotropic (replicating in multiple mammalian cells, including human but not murine cells), polytropic and modified polytropic (able to grow in murine and nonmurine cells) [1].
Then sections were incubated with a rabbit polyclonal antibody against murine CD68 (a marker of mononuclear cells, including monocytes and macrophages) followed by Cy3-tagged goat anti-rabbit IgG (imaged on the red channel).
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