Sentence examples for murine HSCs also from inspiring English sources

The turnover of murine HSCs also drops quite abruptly, but at 4 6 weeks after birth (Bowie et al, 2007; Kim et al, 2007).

All of these reports demonstrated that myeloid-biased murine HSCs have a LT-repopulating capacity and can produce lymphoid-biased HSCs.

These different effects of p40ABL/BCR on murine and human HSC may be due to differences between UCBCs and murine HSCs regarding their "maturation" state.

In contrast to the BCR/ABLs, p40ABL/BCR and p96ABL/BCR allow for myeloid and lymphatic commitment of murine HSCs.

In murine HSCs, TPO-induced STAT5 signaling has been associated with enhanced self-renewal and improved competitive repopulation, in particular in Lnk−/− HSCs which display hypersensitivity for TPO-induced STAT5 phosphorylation [29].

Yang and Baltimore recently showed that cloned mouse TCRs introduced into murine HSCs can differentiate into antigen-specific T cells [13], [14].

Thus, Sca1+/lin− murine HSCs transduced with p40ABL/BCR, p96ABL/BCR and γ-catenin (positive control) were inoculated into sub-lethally (8 Gy) irradiated recipients.

The proliferative status of HSCs also affects their "transplantability" and engraftment.

HSCs also express TLR4, which senses LPS.

In cultured primary murine HSCs, pharmacological inhibition of ATGL, but not HSL, increased RE accumulation.

We have previously reported that the SP subset of murine HSCs accumulates with age.