In addition, making the vector plots interactive by integrating them into multivariate visualisation tools such as GGobi [ 13] would enable techniques such as 'brushing' to be used.
Unlike widespread belief, multivariate tools used commonly, such as support vector machines or searchlight, seem to do a worse job at selecting predictive regions than univariate tools [ 37].
Among other tools (such as multivariate analysis), network theory is proving extremely helpful in this task, as it provides a theoretical framework and useful analytical methods to assess patterns of interaction among several species of frugivores and fruits [5].
As a consequence, advanced data mining tools such as multivariate statistical analysis or the identification of artificial intelligence predictive models using neural networks [ 25] and rule extraction by genetic algorithms can be made available alongside the data itself.
We have systematically analysed codon usage patterns and genomic heterogeneity using a meta-analyses approach that involves multivariate tools and codon usage indices such as relative synonymous codon usage (RSCU) and effective number of codons (Nc) in the studied gene sets.
To deal with large data, D3.js is usually combined with other tools such as Crossfilter [ 89], a JavaScript library that can explore large multivariate datasets in a web browser, or Zoomdata platform [ 110], a solution for fast analysis and visualization of Big Data.
With the rapid increases in processing speed and memory of low-cost computers, it is not surprising that various advanced computational learning tools such as neural networks have been increasingly used for analyzing or modeling highly nonlinear multivariate engineering problems.
Use tools such as the free ClamXav tool; Sophos also produces a free tool for Macs.
Thus, tools such as Adjuvant!
We may need to add to the statistical treatments currently included in MeRy-B, nonlinear unsupervised multivariate methods, such as those based on neural networks, or supervised methods, such as the partial least square (PLS) method, included in tools such as Multi Experiment Viewer http://www.tm4.org/mev/ or MetaboAnalyst [ 40], or other statistical packages or software.
