Multivariate stepwise Cox regression model was performed to identify significant contributors that were associated independently with death on univariate analysis; multivariate risk ratios are presented with 95% confidence intervals.
In a subgroup analysis restricted to 111 articles with negative conclusions we observed a significant independent predictive value of the h-I in multivariate analysis (risk ratio = 1.033; 95%CI, 1.008-1.059; P = 0.009).
Ki-67 LI was also identified as an independent prognostic indicator in a multivariate analysis (risk ratio, 2.021; 95% confidence interval, 1.018 4.010; P = 0.044).
In a prospective study of prostate cancer incidence (127 cases), among 22 320 Japanese men, sleep duration was associated with lower risk; the multivariate hazard ratio of men who slept ⩾9 h per day compared with those who slept less was 0.48 (95% confidence interval: 0.29 0.79, P for trend=0.02).
The study by Chae and colleagues [ 30], which was previously cited on ACEI/ARB, also evaluated the association with statin use and reported a decrease risk of recurrence (multivariate hazard ratio (HR) = 0.40, 95% CI = 0.24 to 0.67) and no impact on overall survival.
Compared to the patients with homogeneous perfusion, these patients were at higher risk for developing allograft dysfunction (multivariate hazard ratio, HR = 5.59).
Multivariate adjusted risk ratios for survival and CKD outcomes were displayed graphically if available.
Eligible prospective studies reporting the multivariate adjusted risk ratios (RRs) for association of n-3/n-6 PUFAs ratio in diet or serum with BC risk.
Since cervical lymphadenopathy was the most common site of lymph nodes in this series, multivariate adjusted risk ratios (RR) were estimated with the RR for cervical region set at 1.
EGFR-retained independent prognostic significance for OS in type II EC when accounting for age and stage in multivariate analysis (EGFR, risk ratio 1.81, 95% CI 1.10 – 2.99, P=0.0197; Table 4).
