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One major reason for use of multivariate procedures for our model is that it keeps Type I error to a minimum (Fan, 1997; Sherry and Henson, 2005; Thompson, 1985 , 1991.
These data were analyzed using hierarchical multivariate procedures for each individual question [ 31].
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Hotelling's T2 chart is the most widely used multivariate procedure for two or more related quality characteristics, but it is slow in detecting small process shifts.
It is a multivariate procedure for detecting natural groupings in data.
The four-way ANOVA analysis was carried out by the GLM multivariate procedure for the CpTI and Bt/CpTI hybrid lineages separately in F2 hybrid progeny.
All analytical procedures accounted for clustering of observations at the practice level using Taylor series expansion procedures for the 2*2 tables and mixed effects models for multivariate procedures [ 21]. 95% confidence intervals (95% CI) of means, proportions and odds ratios were calculated accordingly.
Taylor series expansion procedures were used for 2*2 tables, and mixed effects models for multivariate procedures [ 22, 23].
Unlike most other multivariate procedures, SEM provides precise estimates for measurement errors [ 34].
However, until more comprehensive investigations have been performed for the multivariate procedures, it seems prudent to examine the false positive rate in 1,000 permutations of their data before accepting the results at face value.
We also could not use any multivariate procedures to examine predictors of vaccine uptake for the same reason.
Additionally, extensions of a multivariate procedure can incorporate more complex modeling of the mixture mechanism, for example, including a Hidden Markov Model approach.
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