The association between fresh frozen plasma and infectious complications remained significant in the multivariate model, with an odds ratio of infection per unit of fresh frozen plasma transfused equal to 1.039 (1.013-1.067).
A multivariate model with this covariance structure provides a reasonably good fit to logArea data.
When placed in a multivariate model with HLA-B*57, heterozygosity and homozygosity for the HLA-C5'-C independently associated with disease-retardation (Table 2, compare models 2 and 4).
All cases with missing values for the variables examined were excluded from the multivariate model with 114 patients infected by the Mercian strain and 1,891 patients in the control group included.
However, when examined in the context of a multivariate model with B*57, the hazard ratio for the HCP5 allele was >1 (RH = 2.06; 95% CI = 0.98 4.33, P = 0.056; Table 2, model 5).
We selected the multivariate model with the lowest AIC score.
b Model 1: Multivariate model with individual-level covariates only.
All variables in the multivariate model with P < 0.05 were considered as independent predictors.
The multivariate model with backward manual selection of statistically significant variables was carried out (P<0.05).
Eventually, a multivariate model with all risk factors including VKA treatment was estimated.
The multivariate model with the clinical covariates described above explained 23.9% of this change.
