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None of the co-variates which met the pre-specified p value cut-off for entry into the multivariate model remained after backwards elimination of non-significant predictors.
Variables in the multivariate model remained significant after adjusting for occupation, education and history of chronic diseases.
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The association of metformin with increased OS in the multivariate Cox model remained significant for all these landmarks (Supplementary Table 4).
When the two additional covariates were included stepwise in a multivariate model, both remained significant.
After controlling for interactions among these variables with a multivariate model, leptin remained significantly associated with percentage body fat and the knee osteoarthritis score (Table 3).
In the resulting multivariate model, all remaining variables were considered significant if p≤0.05.
We used Harrell's C-index to estimate predictive accuracies of the multivariate models, which remained at 0.75 whether 5hmC score was included or not (Table 2).
In multivariate models, factors remaining included younger age, lower recent CD4 count, duration of antiretroviral treatment, and living in high TB burden countries.
However, in the multivariate model only KG remained significant.
In the multivariate model, placental weight remained associated with total hCG levels.
When these six miRNAs were included in the same multivariate model, only KSHV-miR-K-12-10b KSHV-miR-K-12-10b KSHV-miR-K-12-10b KSHV-miR-K-12-10b KSHV-miR-K-12-10b
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