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The combined-PI risk predictor had the most significant effect in the final multivariate model (p = 0.004).
Our results demonstrate no significant improvement in patient outcomes over the years in phase III trials of systemic chemotherapy for ED-SCLC, with an increase of 0.021 months (0.63 days) per year (univariate analysis; P = 0.272; Figure 3) confirmed in the multivariate model (P = 0.950; Table 3).
Anti-merozoite IgG levels and clinical outcome for non-parasitized Ndiop inhabitants were correlated after bivariate analysis (P<0.001), but anti-merozoite IgG was no longer significant when age was included in the Poisson regression analysis for the multivariate model (P = 0.91, Table 2).
There was good fit for the multivariate model (p = 0.625).
Hosmer-Lemeshow goodness-of-fit test for multivariate model, p = 0.751.
These trends were stronger in the multivariate model (P = 0.057 and 0.069).
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HR hazard ratio, N number of deaths, ND not done, NS non-significant in the multivariate model, P-Y person-years.
After simultaneous control for risk factors, BMI was the primary contributor of the variation in multivariate models (P < 0.001), followed by age and WBC count (P < 0.001), and family history of diabetes and triglyceride levels (P = 0.12).
bC reactive protein (CRP) was forced in the multivariate models (p values for association with the risk of colorectal cancer were respectively of 0.58, 0.87, 0.60, 0.69 in the NGAL, NGAL/MMP-9, sTNFR-1 and sTNFR-2 models).
Of those, the two diagnoses most strongly associated with increasing soil Cs exposure were codes 281.9, "other deficiency anemias unspecified," and 785.6, "enlargement of lymph nodes," in both univariate and multivariate models (p < 0.05).
The rate of decline in eGFR in patients with low and high leptin levels was significantly steeper than that in patients with midrange leptin levels in both the univariate (P < 0.001 and 0.012) and the multivariate models (P = 0.005 and 0.006) (Fig. 1 A ).
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