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We also fitted a multivariate model considering the indicators simultaneously.
Global model: multivariate model considering status at 6 months based jointly on BADL and IADL assessments.
The most frequent haplotype was taken as the reference and all other haplotypes were included in the multivariate model considering the number of copies of that particular variant.
In a stepwise multivariate model, considering these differences in baseline characteristics stroke / TIA (OR 1.96; 95%CI 1.06-3.62), the presence of heart failure (OR 1.63; 95%CI 1.07-2.49), clinically relevant depression (OR 4.20; 95%CI 2.36-7.46) and sulfonylurea use (OR 1.82; 95%CI 1.25-2.63) remained predictors of hypoglycemia in the elderly (Table 3).
More importantly, the recurrence score was significant in univariate Cox regression and remained significant in a multivariate model considering clinical factors that were significant (P<0.05) in the univariate analysis, namely, preoperative PSA level, Gleason score and TMPRSS2 ERG fusion status (Table 1 – Toronto cohort).
Furthermore, the nine-gene expression recurrence score was significantly associated with biochemical recurrence by itself and in a multivariate model considering the Gleason score and TMPRSS2 ERG fusion status (i.e., those clinical data significant in univariate analysis; Figure 4B, P-value 4.15 × 10−7).
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The initial Cox multivariate model considered the association between BC subtype and risk of death, after adjusting for stage and age at diagnosis.
In a first step the multivariate model considered all relevant risk factors, which were in a second step optimized keeping only CMV reactivation and those factors with a P < 0.05.
PR protein expression did not contribute significant prognostic information to multivariate models considering ER and other standard clinico-pathologic features in the GEM or NHS datasets.
PR expression is not associated with prognosis in ER- breast cancer, and PR does not contribute significant independent prognostic information to multivariate models considering ER and other standard clinico-pathologic factors.
Nevertheless, alternative multivariate models considering TFR instead of contraceptive use revealed two opposite effects of TFR on mortality ratios: while displaying an inverse relationship with MMR and MMRAO, TFR showed a direct association with iAMR, explaining 17.2% of the difference in abortion-related mortality among states.
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