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MDR performs an exhaustive search of all variables and variable combinations to identify univariate or multivariate disease risk models.
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To analyze the independent contribution of the genetic covariates to disease risk, multivariate analysis was performed.
Metabolomics approaches can intrinsically provide holistic molecular perspectives and thereby lead to better representations of disease progression, especially if we stop using univariate cut-offs for diagnostics and start handling disease risk as multivariate continuous dimensions.
The sPLS-DA is a supervised, multivariate technique to determine metabolic groups associated with disease risk.
Neither decreased heart disease risk.
cardiovascular disease risk factors.
Vascular disease risk factors were associated with higher healthcare costs across all countries except Germany, but associations were only maintained in multivariate analysis for the UK (1.2-fold increase, 95 % CI 1.0 1.4) and Spain (1.3-fold increase, 95 % CI 1.0 1.7).
heart disease risk increases.
Disease risks revealed.
Dr. Oz Heart disease risks.
The multivariate relative risk of death from chronic respiratory disease comparing extreme categories of WC was 2.77 (95 percent confidence interval, 1.95 to 3.95; P for trend<0.0001).
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