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Subgroup analyses are hazardous, but in a multivariate analysis restricted to 111 articles with negative conclusions we observed a significant independent predictive value of the h-I.
In multivariate analysis restricted to the 159 patients with known LDH and proteinemia, RPA 2 and 3, Le Scodan's Score 3 and P1PS 2/3 were associated with worse survival.
In a second multivariate analysis restricted to the 159 patients with known serum LDH level and proteinemia, the RPA 2 and 3, Le Scodan's score 3 and P1PS 2/3 were associated with worse survival (Table 4).
In the multivariate analysis restricted to patients with infectious diseases, the exercise variable was the only remaining significant variable, and for patients with musculoskeletal diseases 'sick listing during the last year' remained significant.
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Table 4 summarizes the results of multivariate regression analysis restricted to HCT survivors, examining the relevant demographic, clinical, and treatment-related factors associated with self-reported risky health behavior.
Also the multivariate conditional analysis restricted to clinical centers where all the patients were included confirms that a selection bias is unlikely to explain the association between influenza vaccination and GBS.
In a multivariate survival analysis restricted to ER α, PR (as markers of luminal phenotype) and Mb, only PR remained a significant prognosticator (HR=0.62, P=0.004), whereas Mb yielded a trend towards a prognostic value (HR=0.75, P=0.06) and ER α showed none at all (HR=0.74, P=0.11).
In a multivariate logistic regression analysis restricted to patients without shock, forward selection identified three variables (ratio of arterial partial pressure of O2 and inspired O2 concentration – PaO2/FiO2, base excess and APACHE III scores) in the final model (r2 = 0.37).
While the bi-variate analyses were carried out separately for each route the multivariate analysis were restricted to combined data only.
We a priori adjusted for the potential confounders BMI, smoking, and a recorded diagnosis of diabetes mellitus (or diabetes duration in the sensitivity analysis restricted to diabetic cases and controls) in the multivariate model.
The analysis restricted to children < 15 years of age showed a multivariate RR of 0.78 (95% CI, 0.61 1.01).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com