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Multivariate analysis reached the same conclusion that exposure to carbapenems was the only significant independent risk factor for the appearance of IR-MDRAB (adjusted OR, 1.48; 95% CI, 1.14 to 1.92) (Table 2).
Similar(59)
In the multivariate analysis, age reached the significance level in MW and the whole group, but not in PMW.
Uni- and multivariate analyses included age, tumor size, grade, ER, and Her2; in multivariate analysis, MammaPrint reached near-significance (HR 3.01; p 0.08).
In multivariate analysis, performed colonoscopies reached an OR of 9.9 (CI 95%% 1.16 84.08) for qualifying as appropriate for colorectal cancer (CRC) diagnosis, 1.49 (CI 95%% 1.1 2.02) when requested by a general practitioner, and 1.09 (CI 95%% 1.07 1.1) when performed on women.
15 We used the cut-off of 6% of CPA and the time to first reach CPA≥6% to compare the allocated treatments, including a multivariate analysis: 20 MT patients reached CPA≥6% (20/37 or 54%) at a median of 41 months, while 13 TT reached CPA≥6% (13/44, 30%) at a median of 49 months.
Tumor stage of DTC was also entered into the multivariate analysis because it almost reached significance with p = 0.071.
Grade and ER lost their significance in the multivariate analysis, and only MammaPrint reached near-significance (HR 3.01; p 0.08) (Table 2).> A sub-analysis of MammaPrint in patients with IHC/FISH HR-positive and Her2-negative disease also significantly predicted 10-year DMFS with a HR of 2.91 (95 %CI 0.97 8.68; p = 0.045).
The covariates incorporated into the multivariate analysis were the variables reaching P<0.05 in an univariate analysis.
The screening process aimed to optimize the number of potential predictors to be included in the multivariate analysis in order to reach a satisfactory compromise between making Type I and Type II errors.
The use of corticosteroids seemed to increase the mortality rate, but in the multivariate analysis this association failed to reach statistical significance (OR = 2.2; 95% CI = 0.08 to 6.5, P = 0. 1).
Cardiac disease and SES were the only covariates significantly associated with death in univariate analysis and none of the investigated co-morbidities, immigration status, sex nor SES covariates reached significance in multivariate analysis (data not shown).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com