Using multivariate analysis, the primary tumor group, visceral or cerebral metastases, abnormality of laboratory data, ECOG PS 3 or 4 grade, previous chemotherapy, and multiple skeletal metastases were found to be significantly independent prognostic factors (Table 3).
Multivariate analysis identified primary tumor localization in sigmoid colon, lack of metastases in regional lymph nodes, CEA level within normal limits and good performance status according to WHO criteria (0 1) as favorable independent prognostic factors.
By multivariate analysis, the primary negative determinants of CD were African American race and hyperparathyroidism; whereas, glomerular disease had a positive influence on capillary rarefaction (R = 64.2% variance; P = 0.001).
Multivariate Logistic Regression Analysis: Primary outcome measures included rates of under-triage, over-triage, and concordance (accurate triage).
This finding also held for a multivariate analysis controlling for primary caregiver, hours of care available, and economic status.
The multivariate analysis showed that primary and secondary educations are associated with age, wealth quintile, region and religion.
In a multivariate analysis, a large primary tumour size, the presence of axillary nodal metastases, a high mitotic count and the presence of tumour necrosis all had an independent prognostic value in ILC.
In the multivariate analysis, KRAS status, primary tumor site, and clinical situations for the development of systemic metastasis were significant predictors for liver-only and/or lung-only metastases (Table 7).
The independent factors for shorter OS (multivariate analysis): male gender, primary tumor ulceration, number of involved nodes ≥4, micrometastases size >1.0 mm, and, in additional model including molecular analysis positive MM-RT-PCR results (hazard ratio [HR] 3.2), micrometastases size >1.0 mm (HR 1.13), and primary tumor ulceration (HR 2.17).
