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In a multivariate analysis considering aGVHD as a time-dependent covariate, a significant effect on the incidence of CMV reactivation was noted for HLA disparity (hazard ratio [HR]: 0.54 for 8/8 match compared with 3-allele mismatch) and development of aGVHD (HR: 1.26).
Special consideration will be taken in the multivariate analysis considering the site origin of the study sample.
We performed also a multivariate analysis considering the eGFR and UACR as continuous variables from point considered normal.
By multivariate analysis, considering chemotherapy response, ERCC1 was a negative predictive marker for response rate (adjusted OR 5.038, 95% CI 2.44-10.37, P = 0.001).
These results were confirmed by multivariate analysis considering E-cadherin immunoreactivity in primary cancers and metastases, respectively, and TNM status, tumour grade, histological subtype, and FIGO stage.
This nine-gene expression recurrence score remained significant in multivariate analysis considering clinical factors such as Gleason score and other genetic factors such as TMPRSS2 ERG fusion status.
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Seventh, in contrast to previous cohort studies [ 9- 16] 16], our multivariate analysis considered the number of healthcare visits to minimize detection bias, because HCV-positive patients might have been more closely followed and therefore received earlier diagnosis of CKD.
Multivariate analysis considers the correlations between genes in the pathway and calculates the pathway level statistic directly from the expression value matrix using Hotelling's T test [ 11] or MANOVA models [ 12].
The soil strength data, measured to a depth of 52·5 cm using a recording penetrometer, were corrected to a common water content and then submitted to a multivariate approach consisting of a combination of principal component analysis (PCA) and multivariate variance analysis, considering crop season and sampling date within season as repeated factors.
Since the residents of area 4 showed the highest levels of β-HCH, we conducted a stratified multivariate regression analysis considering two groups: subjects residing in area 4 and those residing in the other 3 sub-areas (area 1 3).
The association of patient- and tumor-related case-mix factors, hospital factors (teaching status, volume), and treatment factors (neoadjuvant therapy, laparoscopic surgery) with being in the high stoma group was assessed with a Chi square test and multivariate logistic regression analysis, considering the same case-mix factors as mentioned above.
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