Adjusting for male sex, rural residence, TB smear status and disease location, and the occurrence of adverse events during TB treatment in multivariate analysis, the benefit of CTX persisted (adjusted odds ratio for unsuccessful outcome 0.1; CI, 0.1 0.3).
Interestingly, a recent study of 842 adults included in candidemia trials did not find on multivariate analysis any benefit from early catheter removal; the expert guidelines remain the best synthesis of all available data, however, and removing the catheter should thus be attempted in all ICU patients with candidemia [ 64].
Although the depth of invasion and the number of organs with metastasis were not found to be independent predictors of survival on multivariate analysis, the survival benefit from gastrectomy with or without metastasectomy should be further evaluated by stratified analysis.
At 9.7 years median follow-up, multivariate analysis showed a DFS benefit for tamoxifen of borderline significance (P = 0.056) and a trend for improved OS (P = 0.12).
Multivariate analysis however showed a significant benefit of perioperative chemotherapy for CLM.
After multivariate analysis, a statistically significant OS benefit was found for patients with MUP over MKP patients.
In the current study, the nonsignificant difference was 4%, although multivariate analysis demonstrated a stronger trend toward benefit in the SLND group (p = 0.09).
Although the unadjusted Kaplan-Meier analysis suggested that GP IIb/IIIa inhibitor use was associated with improved outcomes, multivariate analysis (including propensity scoring) showed no benefit for either survival (P = 0.136) or MACE (P = 0.614).
It also showed no benefit of WBRT in multivariate analysis (Yu et al, 2002).
Significant predictors of long-term benefit of therapy in multivariate analysis were age<65 years (P=0.03), β2-microglobulin <2.5 mg/l (P=0.002) and fewer prior therapies (P=0.002).
