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On multivariate analysis, apart from history of previous uterine surgery, we also found skin color as a protective factor, in contrast to descriptions in the literature reporting nonwhite skin color as a risk for the occurrence of complications and death from ectopic pregnancy.
This is in contrast to a previous smaller study (Ramsey et al, 2008) in which on multivariate analysis apart from clinico-pathological variables and the SSIGN, UISS and Kattan scores, only CRP but not other haematological variables was significant for CSS or RFS.
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Furthermore, a multivariate analysis shows that, apart from age and diameter, the probability of conceiving after myomectomy is higher in case of intramural myomas (intramural versus subserosal: OR 12.382, 95% CI: 1.61 95.22) or laparoscopic surgery (laparoscopy versus laparotomy: OR 14.062, 95% CI: 1.40 141.15).
Most importantly, CYFRA 21-1 washownwn to be independent of CA 19-9 in multivariate analysis, and was – apart from KPS – the only significant prognostic factor for OS in a multivariate Cox model.
After multivariate analysis, all of these factors, apart from the child's head circumference, remained significantly predictive.
Baseline CgA >120 pmol l−1 was the only other risk factor, apart from age, found to be associated with worse OS on multivariate analysis, and only in metastatic pancreatic NENs.
Apart from Topo2 α, the EGFR– status was predictive of pCR in univariate and multivariate analysis in this study.
In multivariate analysis, ER α immunohistochemistry status was independently significant for RFS in the presence of each other parameter apart from grade and Ki67 status.
However, in the multivariate analysis (Table 3), early CBC risk was strongly dependent on tumour extension, whereas late CBC risk was, apart from age, only associated with clinical tumour size (T).
The multivariate analysis included all the significant variables (NA ≤ 135 mEq/L, AP > 1.5 ULN, WBC, HE, and CS nonresponse) confirmed in the univariate analysis apart from the parameters which were calculated as a part of the scoring models.
Apart from fever and cough, myalgias and rhinorrhea were significant associated symptoms of influenza based on multivariate analysis (Table 1).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com