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On multivariate analysis, advanced ovarian cancer (OR, 0.26 (0.10–0.72)) was independently associated with a lower CR.
In the multivariate analysis advanced stage and the status of tumour/stroma cyclooxygenase-2 IDV ratio retained an independent negative prognostic role.
In multivariate analysis, advanced age was independently associated with lower RRvar in both healthy volunteers and diabetic subjects, whereas higher glycated hemoglobin A1c and systolic blood pressure were independently associated with lower RRvar in diabetic subjects.
In multivariate analysis, advanced age and stage, poor performance status, and positive ERCC1 emerged as predictors of worse disease-free and overall survival, as opposed to positive phospho-mTOR.
On multivariate analysis, advanced stage disease (P<0.001), aggressive histologic cell types (UPSC and CC, P<0.001), and older age at diagnosis (P<0.001) were all independent predictors of poorer survival (Table 2).
35 In multivariate analysis, advanced stage of HIV infection (established AIDS), longer duration of HIV infection, low nadir CD4 cell count, decrease in CD4 cell count, and high viral load have been identified as risk factors for lipodsytrophy.
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In multivariate Cox regression analysis advanced preoperative stage predicted reduced long time survival with HR (95%CI) 1.63 (0.92.89.89) and 4.16 (1.9.059.05) for patients in stage IB and II-IV respectively, when compared to patients in stage IA.
Predictors of double diagnosis in multivariate analysis were advanced age and treatment with alpha-receptor blockers and benzodiazepines (Table 3).
On multivariate analysis, hypoalbuminaemia, advanced age, hyponatraemia, male gender (aged > 50) and diffuse large cell or large cell, immunoblastic histology (Working Formulation) had an adverse effect (P = 0.003, < 0.0001, < 0.0001, 0.002, and 0.03).
On multivariate analysis, old age, advanced ECOG performance status, bacteremic pneumonia, and nosocomial infection were independent risk factors of 30-day case fatality.
In this study, our multivariate analysis showed that advanced T stage and CK7+/CK20- were identified as significant independent factors related to survival, and poor differentiation significantly influenced the rate of disease-free survival.
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