However, in multivariate analyses, only study month and study site remained significantly associated with time to starting HAART.
Because this study had an exploratory character and the limited sample size did not allow multivariate analyses, subsequent studies are needed to confirm the findings.
In the multivariate analyses, most studies included only arrest factors, such as 'witnessed arrest', 'bystander arrest' and 'shockable rhythm' in the model; thus, these studies do not clarify the influence of pre-arrest comorbidity and functional status.
(iv) Although we have used multivariate analyses, observational studies cannot exclude residual confounding factors.
After 5 years this factor had no influence on the HHS (Fig. 1).> -wrap-foot> Significant p values are presented in bold NS not significant in multivariate analysis aNumbers too small for analysis bNot entered in multivariate analyses This study calculated the reliability of the HHS with and without the pain score.
Nevertheless, serial assessment of tumor shrinkage (by CT for example) at the time points of OPN readings could enhance uni- and multivariate analyses of further studies but were not available in the present study.
Importantly, we describe the variability of the weights assigned to individual transcripts in multivariate analyses in repeated studies and suggest that the variability we describe may be the cause of inability to repeat many earlier studies.
In the registry cohort, age was not associated with mortality, and this was also the case in multivariate analyses from other studies assessing predictors of death in critically ill patients admitting to the ICU with solid cancers [11, 12, 15 17].
21 Moreover, the logistic regression model of multivariate analyses in some studies might have been overfitted.
Ki-67 remained an independent prognostic factor in multivariate analyses in seven studies (HR 1.05 1.72).
