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In both univariate and multivariate analyses, low age and childlessness at diagnosis were the only variables associated with post-treatment attempts of parenting.
According to multivariate analyses, low systolic blood pressure, low cholesterol level, hyponatremia, hyperkalemia, the use of inotropic agents and norepinephrine were predictive parameters for in-hospital mortality in patients without cardiogenic shock.
In the multivariate analyses, low MMSET (hazard ratio (HR), 0.59; P=0.04) and low UBC9 (HR, 0.52; P=0.01) levels were markers of longer survival to first-line FOLFOX, whereas palliative surgery (HR, 2.47; P=0.005), low BRCA1 (HR, 3.17; P=0.001) and low MMSET (HR, 2.52; P=0.004) levels were markers of shorter survival to second-line docetaxel.
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In univariate CLR analyses, 16 variables achieved significant level, and six of them remained significant in multivariate analyses, including low T score, low BMI, low MMSE score, milk intake, walking difficulty, and significant fall at home.
Multivariate analyses indicate low p53 immunostaining scores and young age to render an approximate two-fold survival advantage; however, low-grade histology per se yielded an approximate nine-fold advantage (Table 3).
In univariate and multivariate analyses, age, low BMD and λ light chain isotype were associated with a significantly increased risk of vertebral fracture (Table 3).
In multivariate analyses, a low number of organs affected by metastatic disease and grade 3+ Her-2/ neu overexpression yielded a reduced risk of death within the observation period (Table 3).
The overall survival of NSCLC patients with low miR-100 was significantly lower than that of those patients with high miR-100, and univariate and multivariate analyses indicated that low miR-100 expression might be a poor prognostic factor.
The adenoma detection rates for these multivariate analyses remain too low to be useful, 22.7% in the Wild study [ 99].
Multivariate analyses showed that low miR-216b expression (P=0.049) and PVTT (P=0.008) were independent risk factors of poor prognosis of patients with HCC (Table 3).
Of interest is also to note that of the socio-demographic factors investigated in the multivariate analyses, partner's low education and lack of assets in the household (as a proxy of socio-economic status) contributed to the risk of current and earlier depression.
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