In uni- and multivariate analyses, high levels of miR-202 significantly correlated with poor overall survival (P=0.0001).
In multivariate analyses, higher levels of PDGF and lower levels of VEGF were associated with elevated regurgitation velocity.
In multivariate analyses, high-level coexpression of HER2 and GATA4 independently predicted DFS (hazard ratio [HR] 8.75, 95% CI 2.20 39.48, P = 0.002).
The key finding of our study is that in uni- and multivariate analyses high serum levels of miR-202 proved to be an independent prognostic factor.
Special attention is given to the use of multivariate analyses in the High Level Trigger.
Multivariate analyses selected high IMD level (OR, 1.089; 95% CI, 1.062 1.116; P < 0.001) and positive lymph node status (OR, 5.691; 95% CI, 2.846 11.379; P < 0.001) as the independent predictors for 5-year adverse event of BC women.
Multivariate analyses defined high serum levels of DKK-1 as an independent prognostic marker in prostate cancer (HR 3.73; 95%CI 1.44-9.66, p = 0.007).
Multivariate analyses established high BCAR4 mRNA levels as an independent predictive factor for poor PFS after start of tamoxifen therapy for recurrent disease.
The Educational level was described as a three group variable (secondary school/university, complete primary/vocational training and incomplete primary); for the bivariate and multivariate analyses; education level was divided into incomplete primary contrasted with higher education.
In our study the multivariate analyses show that higher levels of emotional demands lead to higher odds of bad mental health and bad sleep quality.
Furthermore, in multivariate Cox's regression analyses, high suPAR levels in serum were significantly associated with a 7-fold higher risk of death (of any cause) of PCa patients.
