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Older age correlated with increases in p53 expression and this correlation held up in multivariate analyses, even after controlling for the strongest traditional prognosticator in the clinical setting, histologic grade.
2 Our study suggests that inhaled HS is beneficial in reducing exacerbations across all stages of CF lung disease using multivariate analyses, even though the univariate analysis only showed benefit in mild CF lung disease.
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Even multivariate analyses based on relatively large data sets are thus likely to yield imprecise estimates.
The hypothesis received some support, but the association was relatively weak, in the multivariate analyses the significant effect even disappeared.
This somewhat unexpected effect is also seen in the multivariate analyses, which showed that even though the explanatory capacity of the EPI-Q score was limited, the influence when the participants were divided into groups were significant; the high EPI-Q group had a higher improvement in OHRQoL than the low group.
The results reveal that the proposed method gives better results depending on whether or not the data set is multivariate normal even though multivariate analyses require checking the multivariate normality.
In multivariate analyses, this interaction remained significant even after adjusting for other prognostic factors and KRAS status.
However, we recently showed that arterial stiffness measured by brachial pulse wave propagation was associated with IL-18 levels and components of the metabolic syndrome, even in multivariate analyses, both cross sectionally and during three years follow up [ 55].
Multivariate analyses in populations with a more even distribution of patients with myopia are needed.
In the multivariate analyses the choice of treatment has no impact on survival, even when including BSC.
However, only frailty held prognostic value for mortality, even after adjusting for confounds in the multivariate analyses.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com