With multivariate adjustment for medical factors, adjusted odds ratios for ethnicity and ISE were 2.01 (CI: 1.39 – 2.92) and 2.84 (CI: 2.09 – 2.85), respectively.
Exposure measures included spot urine samples for both studies; however, Tellez-Plaza et al. (2008) used multivariate adjustment for creatinine to adjust for urine dilution effects, whereas Whittemore et al. (1991) directly adjusted UCd measurements for specific gravity.
As expected, patients with residual thrombus on follow-up ultrasound were at higher risk of recurrence, which remained significant after multivariate adjustment for age, gender and malignancy (adjusted HR, 2.2; 95% CI, 1.15 to 4.17).
A logistic model was used to assess the association of subclinical hyperthyroidism with dementia, Alzheimer's disease and vascular dementia crude, adjusted by age, with a multivariate adjustment for age and BMI.
After multivariate adjustment for birthweight, cesarean section, placental pathology and chorioamnionitis, a strong association remained between the presence of breech presentation and neonatal mortality, with an adjusted OR of 2.2 (CI=1.36–3.63; P<0.01).
Multivariate adjustment for confounders was performed with a Cox proportional hazards model.
The effect was not influenced by multivariate adjustment for cardiovascular risk factors or metabolic traits and, importantly, intake of diuretic medication pointing to a largely independent genetic effect.
This variation in the mitochondrial genome was an independent predictor of AMD following multivariate adjustment for well-known nuclear genetic factors.
After multivariate adjustment for GVHD, CMV serostatus and neutropenia, only the association between the TLR4 1063and and IFNG 874T>A combination and IA remained statistically significant (p = 0.044).
Multivariate adjustment for known prognostic factors was performed using a Cox proportional hazards regression model that included grade, age (<65 years versus ≥65 years), stage (early stage 1 or 2 versus advanced stage 3 or 4), debulking status (optimal, less than or equal to 1 cm.; or suboptimal, greater than 1 cm. residual disease) and 19-gene profile risk status (low- vs high-risk).
Associations were attenuated after multivariate adjustment for tumor-related factors.
