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Our method consists of a paired Cross-normalization (CN) step followed by a modified sign Wilcoxon test with multivariate adjustment carried out for each variable.
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Multivariate adjustment of effect sizes was carried out by 57 studies (31.3%).
However, after multivariate adjustment, this association was no longer significant, with a multivariate adjusted HR of 1.11 (95% CI 0.87 1.41).
Multivariate adjustments for continuous variables were carried out by covariance analysis.
After multivariate adjustment, the aHEI, aMED, and DASH scores were significantly associated with reduced risk.
After multivariate adjustment, diabetic persons had a wider CRAE (145.23μm vs 142.38μm, P<0.001).
After multivariate adjustment, diabetes remained associated with lack of complete STR and mortality at 6 months.
After multivariate adjustment, ESA use in 1026 patients was associated with greater odds of stroke (odds ratio 1.30).
After multivariate adjustment, anemia at PICU admission was the strongest risk marker of anemia at PICU discharge.
These estimates also shifted towards the null after multivariate adjustment.
After multivariate adjustment, the linear relationship was still present.
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