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To determine the correlation between miR-4516 expression and overall survival of patients with GBM, total RNAs were isolated from 268 FFPE tumor samples, miR expression was assayed (simultaneously) using the nCounter human miRNA v3a assay followed by univariable and multivariable survival analyses.
In this cohort, in multivariable survival analyses both plasma big ET-1 and plasma BNP (brain natriuretic peptide) were related to mortality, and combined mortality and morbidity (median follow-up: 23 months) [29].
Univariate and multivariable survival analyses were performed.
Multivariable survival analyses were done using Cox regression analyses.
Multivariable survival analyses are generally carried out using Cox regression.
Subgroup univariable and multivariable survival analyses on ER-positive cases were conducted similarly.
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The proportional hazard assumption was evaluated and satisfied for all bivariate and multivariable adjusted survival analyses.
Also, this is one of the few studies that have used multivariable and survival analyses for investigating adverse pregnancy outcomes such as chorioamnionitis and PTB.
We used multivariable competing risks survival analyses to determine the association of the plausibility of infection with mortality.
Multivariable 5-year survival analyses were conducted to discriminate independent risk factors for death, expressed in relative excess risk of dying (RER).
Multivariable survival and logistic regression analyses will be used to assess the effect of the treatment groups on the outcomes after adjusting for covariates.
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