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Welfare indicators with an association significant at P < 0.05 were then taken forward to a multivariable reduction step, using the same methodology.
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After multivariable adjustment, the reduction in the risk of malignancy remained significant (adjusted hazard ratio 0.60, 95% confidence interval 0.39 to 0.93; P=0.02) (table 2).
However, when we adjusted for F0 maternal age and parity in a multivariable model, the reduction in age of first delivery that was associated with prenatal famine exposure was not attenuated (unadjusted HR 0.8, adjusted HR 0.8 [95% CI 0.6 1.0]).
We produced a best fitting, parsimonious, multivariable model with variable reduction by Akaike's information criterion.
In a multivariable analysis after stepwise reduction, WBC count and CRP remained significantly associated with EONI (Table 2).
Following variable reduction using multivariable regression, another 10 indicators were excluded leaving 18 potential welfare indicators for the systematic selection procedure [ 7].
This association was, however, no longer detectable in models adjusted for changes in low density lipoprotein cholesterol (bivariable or multivariable), indicating that the apparent reduction in outcomes was due to the association of changes in high density lipoprotein cholesterol with changes in low density lipoprotein cholesterol.
Multivariable analysis revealed a significant RR reduction in ulcers of ∼55% with HZT-501 after adjustment for risk factors that may influence the development of ulcers, such as age, ulcer history, aspirin use, and baseline erosions.
Multivariable-mixed effects analysis demonstrated a reduction in 0.1 visits per 6-month period following surgery overtime (p < 0.001).Mastoid obliteration may be valuable in the management of the well-developed and chronically wet mastoid cavity, particularly when the drainage emanates from mucosal disease or cell tracts in a deep sinodural angle.
This mortality reduction remained significant in a multivariable model that controlled for other potential explanatory variables.
Chemotherapy and oophorectomy were both associated with reductions in mortality in the multivariable analysis, but neither of these associations was statistically significant.
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