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Multivariable modelling showed the frequency of DKA was inversely associated with gross domestic product, latitude and background incidence of type 1 diabetes.
Multivariable modelling showed that decreased health-related quality of life (HRQL) was associated with increased age, female gender and increased body mass index.
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All variables in the multivariable model showed VIF < 2, suggesting no collinearity.
The multivariable model showed that APACHE IV scores, plasma lactate levels and arterial pH significantly confounded the relationship between the group stratification and in-hospital mortality (Additional file 1: Table E4).
The multivariable model showed a c-statistic of 0.66 (95% CI: 0.64 0.68) and very good calibration (Hosmer Lemeshow χ=7.63, P-value=0.57).
The multivariable model showed a lower L/N ratio (p < 0.001) and an absence of extranodal growth pattern (p = 0.05) to be independent predictors of longer DFS.
The multivariable model showed that patients with low health literacy have significantly higher anxiety levels than people with adequate health literacy.
The results were similar to those in men, although the multivariable models showed a marginally significant decrease in the MRR of area-level stress.
Variables included in the final multilevel multivariable model showed either statistical significance (α ≤ 0.05), or evidence of acting as a confounding variable (20%% or greater change to other statistically significant model coefficients when removed).
In assessing the combined effect of neuropathological variables on functional disability, the multivariable model showed that advanced age (>84 years) and neuronal loss showed increased severe functional disability independently of each other, though other factors were still at increased risk.
Subgroup analyses that used the same multivariable model showed a similar protective effect for fluoroquinolones against isolation of each of the three pathogens considered individually, though in the smaller two subgroups the results did not achieve significance.
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CEO of Professional Science Editing for Scientists @ prosciediting.com