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Though differences of opinion exist, some authors have argued that multivariable analysis requires at least 10 outcome events per independent variable to avoid overfitting [ 52, 53].
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Linda Onnen, Global Marketing Director of GE Intelligent Platforms, told me recently by phone that Big Data allows for precisely the sort of multivariable analysis required to identify those links and then analyze them to generate actionable intelligence.
The inclusion of variables with a strong spatial component in the multivariable analysis required the application of an analytical method that could account for the dependence of the network data due to both the inherent nature of the network data and the spatial definition of the link.
Therefore, the results of the multivariable analysis should be interpreted with caution and require further validation.
The limited number of SSIs required combination of the 2 groups in the multivariable analysis.
Multivariable analysis was based on patients having information on all the study variables required for model building (significant on univariable analysis or having biological significance).
Multivariable analysis.
Design: Cross-sectional multivariable analysis.
Most importantly, the association with rs715212 is noteworthy (FPRP <0.2) and approaches genome-wide significance in multivariable analysis (P multivariable = 5.37 × 10−8).
A multivariable analysis of risk factors for PEP was performed.
Variables with P < 0.05 were included in the multivariable analysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com