In multivariable analysis, increasing deprivation remained strongly associated with lower odds of radiotherapy or surgery (odds ratio 0.92 (95% confidence interval 0.90 to 0.94), P<0.001, and 0.91 (0.87 to 0.94), P<0.001, respectively, per incremental deprivation group).
On step-down multivariable logistic regression analysis, increased heart rate, hematocrit and BUN, decreased temperature and hemoglobin, and presence of a mental status change were found to be the strongest predictors of death (Table 2).
In the multivariable logistic regression analysis, increased age, male sex, BMI, waist circumference, systolic blood pressure, and positive family history of diabetes in a first-degree relative were significantly associated with the presence of undiagnosed type 2 diabetes (Table 2).
In addition to statistical significance in multivariable analysis, GGT increased the discrimination of a multivariable base model and improved the clinical net benefit.
Multivariable analysis identified increased NLR (≥3.6) and ANC (≥5300/ μL) as independent prognostic factors for RFS (hazard ratio (HR) = 4.01, P = 0.018) and (HR = 4.71, P = 0.045).
The final model from multivariable analysis included increasing herd size and increasing regional average number of cattle per dairy herd as continuous scaled variables significantly associated with C. burnetii seropositivity (Table 2, Model A).
In multivariable analysis, male gender, increasing age (up to 85 years) and increasing Charlson comorbidity scores were found to be associated with an increased risk of cancer.
According to the multivariable analysis, females showed an increased hospitalization risk (OR: 1.46) and an increased number of days with reduced activities (REND: 1.73) in the population aged 20 44, whereas they had less hospitalizations (OR: 0.70) in the population aged 45 64, as compared to males in the same age class (Tables 2 and 3).
In the multivariable analysis including all samples, increased carriage was still observed for individuals on ART, but results were nonsignificant (aRR 1.22, 95% CI 0.95 1.56) (Table 2).
