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Mitchell continued to refine the design until his death from cancer in 1937, whereupon his colleague Joseph Smith took over as chief designer, overseeing the development of the Spitfire through its multitude of variants.
Interpretation of the multitude of variants obtained from next generation sequencing (NGS) is labor intensive and complex.
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It follows that the major burden of disease is carried by a multitude of rare variants — ones too rare to have been programmed into the SNP chips.
There are a multitude of acronyms, variants with different sequences and parameters, using design features unique to each manufacturer.
One paradigm that allows for the systematic investigation of false memories-directed forgetting (DF -has been investigateDF -hasmultitude of design variants and populations.
Technical flow devices are usually optimized by using numerical algorithms that analyze a multitude of design variants for the flow restraining geometry until an optimum solution is found.
Due to slipped strand mispairing within the 5'-VNTR region that encodes the poly-ψ-domain, a multitude of NeuO variants can be generated and so far, heptad numbers between 1 and 31 (corresponding to 3 to 93 nucleotide repeats) were observed in naturally occurring isolates [13].
2008 The physiological implication of the multitude of splice variants and their differential coupling to signal transduction cascades remains unclear.
A multitude of sequence variants within each toxin class contributes to this heterogeneity and the number of small, multidisulfide-bridged animal neurotoxins may total several million [35].
Nevertheless, these exome and whole-genome sequencing approaches also reveal a multitude of novel variants and VUS for which clinical relevance is uncertain.
A decade of GWAS studies have revealed a multitude of common variants associated with various traits and diseases, each of which seems to contribute to or at least to increase the probability of a phenotype by a small amount [ 65].
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