Sentence examples for multitude of substrates and from inspiring English sources

However, chymases are relatively promiscuous in terms of cleavage specificity, and they have the capacity to cleave a multitude of substrates and can even cleave the same substrate at multiple positions.

With the multitude of substrates targeted and the numerous processes involved, it is not surprising that aberrations in this pathway have been implicated in the pathogenesis of many diseases, such as cancer and, more specifically, breast cancer (Lipkowitz, 2002; Ohta and Fukuda, 2004; Mani and Gelman, 2005).

The GST family of enzymes comprises a long list of cytosolic, mitochondrial, and microsomal proteins which are capable of multiple reactions with a multitude of substrates, both endogenous and xenobiotic.

ABC proteins are primary transporters that mediate the energy-driven transport of a large and diverse multitude of substrates across biological membranes.

Bar coater 08, coating rods are used primarily to apply a variety of coatings or emulsions to a multitude of substrates.

The multitude of substrates makes this task difficult due to the risk of side effects.

At the moment, it is not well understood how the activation of such a ubiquitous pathway, with a multitude of substrates, can have the very specific cellular outcomes observed in a variety of cellular model systems.

Akt contributes to malignant transformation and/or tumor progression by acting on a multitude of substrates (for recent reviews see refs. 4, 26- 28) including IKKα, Bad, caspase-9, and forkhead transcription factors.

14-3-3 proteins play diverse physiological roles and interact with a multitude of substrate proteins during normal development and adulthood [ 25, 26].

Cytochrome P450s (CYPs) represent a large class of heme-containing enzymes that catalyze the metabolism of multitudes of substrates both endogenous and exogenous.

In this way, RSK proteins link MAPK signaling to a multitude of substrate proteins.