The extracellular matrix (ECM) is a fibrillar protein-based network, the physical and chemical properties of which can influence a multitude of cellular processes.
As Arp2/3 controls a multitude of cellular functions51, it may have opposite functions in tumour growth and invasion/metastasis, respectively.
We have recently determined that a multitude of cellular and molecular changes, not surprisingly, occur in the laryngeal mucosa of mice and in laryngeal cell cultures exposed to conventional cigarette smoke.
Rho ROCK signaling is involved in a multitude of cellular processes including migration, morphogenesis, cell adhesion, and cell-cycle progression through mediating cytoskeletal dynamics [136, 137].
Phosphorylation and dephosphorylation of proteins control a multitude of cellular processes.
The proteasome is the major proteolytic complex, responsible, in eukaryotic cells, for the degradation of a multitude of cellular proteins.
To date, the involvement of Ca2+ signaling in a multitude of cellular pathways has been well documented [17].
The regulation of this degradation has been found to be exceptionally complex and dependent on a multitude of cellular inputs.
Once in the cytoplasm, the siderophore is degraded, releasing the iron for use in a multitude of cellular processes including respiration, gene regulation, and environmental sensing [5].
The inflammatory process involves a multitude of cellular interactions between local tissue components, invading cells of the immune system and the peripheral terminals of nociceptive neurons (nociceptors).
Despite our failure to detect an in vivo phenotype when overexpressing the Rbf1N fragment it may be that this region of Rbf1 is nevertheless critical for a multitude of cellular functions.
