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The ramification of the results for a microstructure-based multistage model that comprises crack incubation, small crack growth and long crack growth is discussed in detail.
To sum up so far, with the simple model of constant transition rates between stages, the standard approximation for the multistage model that has been applied to cancer [ 8] yields a constant log-log acceleration of n-1 that is independent of age.
In summary, humans show a consistent increase in the risk of nearly all cancer types with increasing height, and the magnitude of this effect is consistent with what is predicted from a simple multistage model, that is, it is independent of tissue type and of a magnitude consistent with expectation.
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The multistage models that are now used include only terms corresponding to the mutagenic stimuli and thus fail to adequately describe incidence at high dose rates.
These convex relaxations are then extended to multistage problems with model switches between the stages.
These data establish parameter values for a biologically based, multistage cancer model that is then used to predict cancer risk at low exposure levels.
71, 72, 75 Typically, in such models genomic instability is added to a multistage framework that essentially represents an extension of the concepts used in both the stochastic TSCE model and the Armitage Doll model.
To study radiation effects using a combined cell cycle and multistage clonal expansion model that includes processes of damage, repair, apoptosis, and mutation.
Model predictions were made using a steady-state, multistage, equilibrium adsorber model that was previously developed for and integrated into OLI Systems Environmental Simulation Programm (ESP).
The fatigue behavior of a polycarbonate (PC) thermoplastic material was experimentally investigated and modeled using a MultiStage Fatigue (MSF) model that evaluates fatigue crack incubation, Microstructurally Small Crack (MSC) growth, and Long Crack (LC) growth.
We begin by presenting a theoretical framework (i.e. the multistage color vision model) that would help account for perceived differences in blue and red saturation discrimination abilities.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com