To study radiation effects using a combined cell cycle and multistage clonal expansion model that includes processes of damage, repair, apoptosis, and mutation.
This phenomenon of multistage contraction and expansion may be due to the support ring built around the 3-D printed material, which holds the perpendicular layers in place, beginning to absorb and displace energy acting as a multistage spring.
79– 82 Spontaneous cancer incidence in humans over the age range of 20 70 years is typically described very well, marginally better than by the previously discussed multistage models without clonal expansion, although the small differences in quality of fit are typically not statistically significant.
The tribo-test results indicated that the lubricity of the coating-based lubricants is influenced by the interface temperature, the surface expansion and the multistage operations.
Historically, analysis of statistical data on cancer incidences first led to the Armitage Doll multistage model which did not incorporate clonal expansion (Nordling, 1953; Armitage and Doll, 1954).
A notable feature of these predictions is that the number of tumour suppressors (or equivalent) is not expected to be large, plausibly ranging from about 1 to 5 tumour suppressors (i.e. 2 10 mutational steps in a multistage model), although the occurrence of significant clonal expansion (see next paragraph) could raise the upper limit.
The degree of malignancy increases with successive rounds of mutation acquisition and clonal expansion forming a two-stage or a multistage process of carcinogenesis and tumor progression.
During compression, a new phenomenon described as a multistage collapse in which the samplesundergo multiple stages of contraction and expansion was observed as the impact load was applied.
This paper proposes four configuration strategies of expansion liquefaction cycle for distributed-scale LNG plant, namely multistage expanders, single precooling cycle, regeneration and mixture working fluid.
In particular, single stage axial flow turbines, a cheaper option compared to multistage solutions, can be used due to the moderate enthalpy drop in the expansion process.
