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Complex cells with a nucleus (eukaryotes) display a tightly controlled multistage cell division cycle.
Here, a system of Itô stochastic differential equations with linear diffusion coefficients that is based on a deterministic model of multistage cell lineages is investigated.
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The multistage, single-cell assay reported here offers a throughput in the electrophoresis stage (5 min handling time) of ∼30 cells/min demonstrated for 153 cells total.
We have used the Rip1Tag2 (RT2) mouse model of multistage pancreatic β cell carcinogenesis to investigate the contribution of BMDC to tumor angiogenesis and lymphangiogenesis [19].
Cathepsins have recently been shown to be upregulated in multistage pancreatic islet cell tumor model where they contributed to invasive tumor growth [32], [33].
The models discussed above deal with the generally prolonged multistage process whereby a cell and its offspring successively accumulate mutations which result in the production of a cell with a malignant phenotype.
The long latency and distinct multistage process of malignant cell transformation induced by the human mycoplasmas closely resemble human tumor development in nature.
Metastasis is itself a multistage process whereby cancer cells from the original tissue location (the primary tumor) are able to colonize other sites including distant organs (Hanahan and Weinberg 2011).
To study radiation effects using a combined cell cycle and multistage clonal expansion model that includes processes of damage, repair, apoptosis, and mutation.
In this work, we report on the isolation and identification of a resident yeast species in a SSL ethanol plant that operates in multistage continuous mode with yeast cell recirculation using a mixture of spruce (Picea abis) and pine (Pinus sylvestris) hydrolysate.
These data encourage the development of vaccine technologies that can induce strong antibody and T cell responses against multistage malaria antigens in order to achieve maximal protective efficacy.
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