Sentence examples for multistage carcinogenesis process from inspiring English sources
Chemoprevention is defined as the administration of agents (drugs, biologics, and natural products) that modulate (inhibit) one or more steps in the multistage carcinogenesis process culminating in invasive adenocarcinoma of the prostate.
The degree of L1 hypomethylation varies at each locus of each tumor and may change throughout the multistage carcinogenesis process.
Cell proliferation has often been found to be associated with carcinogenesis in rodents and humans at different stages of the multistage carcinogenesis process.
The etiology of breast cancer is complex, and is likely to involve the actions of genes at multiple levels along the multistage carcinogenesis process.
These data indicate that rexinoid bexarotene prevents the development of ER-negative mammary tumour at the early stages during the multistage carcinogenesis process in MMTV-erbB2 transgenic mice.
In addition, a multistage carcinogenesis process has been demonstrated for the rat bladder using MNU or FANFT as initiators, and dietary sodium saccharin, sodium cyclamate, or tryptophan as promoters.
This finding might imply that stromal changes are a late and possibly surrogate event in a process of multistage carcinogenesis and local invasion.
In this context, an HCC lesion which is highly associated with inflammation caused by either hepatitis viruses or drugs is developed through a process of multistage carcinogenesis, i.e., from inflammatory lesions (e.g., hepatitis, cirrhosis and precancerous lesion) to adenomatous hyperplasia, and eventually into HCC.
The Rip1-Tag2 is an orthotopic model of multistage carcinogenesis, believed to better reflect the stepwise process of tumor development via distinctive stages, than conventional subcutaneous models with injected tumor cells.
The transgenic RIP1-Tag2 mouse is an orthotopic model of multistage carcinogenesis and believed to better reflect the stepwise process of tumor development via distinctive stages, than conventional subcutaneous models with injected tumor cells [19], [23].
The deregulation of metabolic process is key event during multistage carcinogenesis.
