The cost of individual treatment for each calf was calculated by multiplying the number of individual treatment days by the average cost of one individual treatment day.
The cost per CVD-free year of life gained was calculated by multiplying the annual cost of treatment by the person-years of treatment plus, for Framingham screening, the cost of a Framingham risk assessment multiplied by the number of assessments, all divided by CVD free life-years gained.
The total cost of each medication was calculated by multiplying the daily cost of treatment by the total number of days of treatment used in each arm.
If the original trial analyses had not adjusted for clustering, we planned to adjust the results for clustering by multiplying the standard errors of the treatment effect by the square root of the design effect.
The internal defects are represented by the level sets, while the shear-locking effect is eliminated by a special treatment, multiplying the shear terms by a factor.
The average cost of managing a new smear-positive patient from diagnosis to completion of treatment for each site was calculated by multiplying the average cost of each treatment component by the number of times the cost was incurred according to the site-specific clinic protocols.
Normalizations were calculated by multiplying the count values in each treatment by the experiment-wide average over the treatment sum.
An entry error may result in a misplaced decimal point or an extra zero or two in the number of treatments, multiplying the cost 10 or 100 times.
The mortality reduction for each treatment for the number of patients in each group, stratified by age and sex, was calculated as the age-specific case death in that group multiplied by the relative mortality reduction reported in published meta-analyses multiplied by the treatment uptake (the proportion of patients receiving that specific treatment, appendix).
QALYs were obtained by multiplying the life expectancy in each treatment arm by the utility (or quality of life score) of the underlying condition.
