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Any nasties in the gut or lungs have to cross the walls of those organs before they can multiply inside the body.Dr Nochi's genetic engineering involved growing the vaccine in rice.
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, manifests discreet strategies to subvert host immune responses, which enable the pathogen to survive and multiply inside the macrophages.
Other bacterial predators either attach to their prey in order to digest them and absorb nutrients, such as Vampirococcus, or invade another cell and multiply inside the cytosol, such as Daptobacter.
These genes confer the organism broader capacities to cope with the oxidative stresses and may necessarily contribute to the abilities to multiply inside the host cells (e.g. macrophage cells), and further the virulence of the bacterium.
First isolated from pulmonary lesions of foals by Magnusson in 1923 [4], R. equi is able to infect, survive, and multiply inside the host cells, mainly in alveolar macrophages [5].
The principal target organ is the liver, where the bacteria multiply inside the hepatocytes.
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Together, these results show that Hfq is important for two hallmark features of adherent-invasive Escherichia coli strains, namely their ability to invade epithelial cells and the capacity to survive and multiply inside macrophages.
The brucellae disseminate or spread via the blood and lymphatics where they multiply inside phagocytes and cause bacteremia.
Setting:Mycobacterium tuberculosis (MTB) is known to adhere to, invade, multiply inside, and modulate respiratory epithelial cell functions.
Xanthomonas enter host plants through surface wounds or natural openings and multiply inside plant tissues (reviewed in detail in [ 4]).
It multiplies inside the cancer cells, bursting them from within.
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