As complex a task as gene sequencing is, charting the multiplicity of interactions that are possible among the roughly 30,000 genes that make up the human chromosome is even more complex.
The relationship between inland ports and regional development is obviously present, but ambiguous since it involves a multiplicity of interactions among a diversity of actors.
This difference may be explained by the fact that bivariate linear analyses do not consider the multiplicity of interactions between all variables like RDA do.
This result is not surprising, considering the multiplicity of interactions among "local" ecological characteristics, environmental factors, and topographic and textural conditions in each specific slope environment.
Accordingly, it could be assumed that - because of the "one-domain" appearance of the LSU and because of the multiplicity of interactions of LSU r-proteins - inactivation or depletion of single LSU r-proteins could result in a more common maturation phenotype rather than distinct ones.
The multiplicity of interactions mediated by Pat-C suggests that these interactions might be synergistic or antagonistic and thus may have a regulatory function as discussed below.
In other words, to look at consent as more than a one-time event because the process involves a multiplicity of interactions between the key actors involved [ 14– 17].
The multiplicity of interactions mediated by Pat-C suggests that certain of these interactions are mutually exclusive and, therefore, that Pat proteins switch decapping partners allowing transitions between sequential steps in the mRNA decapping pathway.
For example, genistein has been shown to evoke G2-M cell-cycle arrest in cancer cell lines [ 18, 19] via a multiplicity of interactions, including an inhibition of Cdc2 activity.
Thus, the multiplicity of interactions, with Aplip1 dimers binding to two SH3 domains of RBP as well as to KLC, might form transport complexes of sufficient avidity to ensure tight adaptor cargo interaction and prevent premature capture of the scaffold components.
The pleiotropic nature of WRN and the multiplicity of interactions make very difficult to determine the prominent biological function of this protein and to correlate loss of a specific activity, meant as biological and not only enzymatic, with the cellular and organismal premature senescence that characterizes the WS syndrome.
