Although the data reflect in situ assessment practices, there is a need for more systematic investigations that look across all cognitive skill levels to further elucidate relationships between cognitive skill level and item difficulty and identify the multiplicity of factors affecting item difficulty, including student epistemologies.
Many philosophers today think that this concept of multiplicity, despite its difficulty, is revolutionary.
In fairness, the obstacles are many: incompetency, corruption, the sheer complexity of disbursing huge sums, the multiplicity and difficulty of the tasks at hand — defense, education, health, prisons, courts, police, disaster relief, regulation of markets, banks, drugs, food safety.
The complexity of waste manifests in the difficulty and multiplicity of its definition and description, which is also contingent on who is looking at the subject matter: ordinary citizens, technicians, businessmen, politicians, activists (Progracz 2002).
The multiplicity of LMW-GSs and the difficulty in distinguishing LMW-GSs from gliadins in SDS-PAGE have complicated efforts to understand the physical and genetic organization of the chromosomal loci containing LMW-GS genes.
However, the multifactorial nature of trauma hemorrhage, the multiplicity of interventions, issues with trial design, difficulties with the conduct of trauma trials and lack of a coordinated approach mean that only limited conclusions can be drawn.
This multiplicity of biological activity, combined with the difficulty of maintaining a stable, effective concentration of the compound in the bloodstream, makes it impractical as a potential medicine.
Informality, on the contrary, introduced into the theoretical debate from the 60s onwards, is a concept that is defined, interpreted and conceptualised with great difficulty, due to the multiplicity of urban, social, cultural and economic meanings it can have.
Many exciting discoveries in glioma genomics have already been made, although a major challenge is the multiplicity of pathways activated in cancer and the difficulty of identifying the key targets in them.
One of the reasons for the level of difficulty of such a task is the multiplicity of all possible risk factors and patient outcomes, as well as their levels of variability and inter-dependence or interrelationships.
One of the fundamental difficulties in engineering design is the multiplicity of local solutions.
