Since the frequency or dose of the different intervention components was not always clearly described in the studies or sometimes somewhat confusing because of the multiplicity of the components tested, we could not draw any conclusions on which intervention dose suits each component best.
The study of bacterial extracts, which are easier to use and analyze as compared to living pathogens, is complicated by the multiplicity of their components.
The complexity of this pathway is increased by the multiplicity of its components.
The multiplicity of cellulosomal components in C. clariflavum and their possible interactions and interconnectivities observed gives rise to the formation of diverse complexes that enable efficient cellulose degradation.
Given the complexity and multiplicity of the components of the pathway and the variety of tumour types affected, in our view, the term 'BRCA-ness' is limiting as it tends to be associated with breast and ovarian cancer, whereas the therapeutic scope for the synthetic lethality of PARPi is potentially much wider.
The last constraint restricts that, since a motif can be inserted many times, the multiplicity of every component should be equal to the multiplicity of the first component.
Existing approaches usually employ a global threshold to remove erroneous k-mers and branches if the multiplicities of these components are smaller than the threshold.
The role of BRAF mutations in the MAPK pathway is complicated not only by the multiplicity of signaling molecular components but also the variation of kinase activity for different BRAF mutants (Fig. 1).
It exhibits varying power demand from a multiplicity of electrical circuits and components which are influenced by changing operational modes, while the electrical supply comes from an energy storage device (usually a battery).
