Sentence examples for multiplicity issues of from inspiring English sources

The authors extended this consistency concept to other situations (Alosh and Huque, 2010), including how to address multiplicity issues of a composite endpoint and its components in clinical trials (Huque et al., 2011).

The hierarchical approach of primary end points avoids multiplicity issues with adjustment of type I error because the second co-primary end point is tested only if the first is statistically significant at 0.05.

Genomic epidemiology has been more eager to adopt explicit consideration of multiplicity issues, which has led to a more uniform adoption of rigorous standards for what is considered appropriately replicated and credible as an association.

The multiplicity issue (inflation of type I error) due to the analysis of three end points will be addressed using the fixed-sequence testing method.

When more than two groups are compared, however, a global p value for the test of the null hypothesis of equality of a parameter (eg, mean or proportion) in all groups can be obtained without raising multiplicity issues (ie, the possibility of finding a statistical difference by chance when performing multiple comparisons).

In Section 6, Yoav Benjamini shows how the false discovery rate (FDR) can be used to tackle some of the multiplicity issues arising when reanalyzing data.

Due to the observational nature of the study, we did not perform adjustments for multiplicity issues within endpoints or for multiplicity caused by multiple endpoints.

Multiplicity issues were dealt with by a priori ordering of the hypotheses.

Our use of the Lasso approach provides an efficient and appealing method for handling multiplicity issues.

Three approaches were adopted to mitigate the multiplicity issues.

Most trials are affected to some extent by multiplicity issues.