The ability to regenerate the microarrays and to analyze more than 30 patient sera consecutively in a fully automated fashion on a single array makes this system unique among the various multiplex systems that have been developed.
However, there has been no available multiplex PCR system that is optimized for NGS analysis of forensic STR markers.
The Magpix is a multiplex immunoassay system that uses magnetic bead technology, with LED optics and charge-couple base device (CCD) camera to illuminate and detect differentially fluorescent dyed beads.
In this study, we developed a multiplex immunoassay system that combines the suspension and planar microarray formats within a single layer of polydimethylsiloxane (PDMS) using soft lithography technology.
To evaluate the contribution of coinfection to the mortality observed in Argentina, we examined 199 cases of previously-diagnosed H1N1pdm infections from Argentina, including 39 cases classified as severe and 160 cases categorized as mild, using MassTag PCR, a multiplex PCR system that assesses 30 to 40 microbial agents in a single reaction [6].
We developed a multiplex barcoding system that allows simultaneous sequencing and analysis of multiple samples using Illumina's platform.
Quansys Biosciences have developed the Q-Plex, a multiplex ELISA system that prints capture antibodies as an array in a single well.
Recently, Soda et al (2012) reported the development of a multiplex RT PCR system that was able to detect EML4-ALK mutations in 4 out of 35 sputum samples, which were part of a prospective screening cohort of NSCLC patients.
The technical feasibility (pre-FEC BER<3.8×10−5) of an unamplified 4×100 Gb/s wavelength division multiplexed direct-detection optical orthogonal frequency division multiplexing (OFDM) system that uses electro-absorption modulators is numerically demonstrated for 2 and 10-km reach of single-mode fiber in C-band.
The cobas MPX (Roche Molecular Systems, Inc., Branchburg, New Jersey) is a recently developed multiplex qualitative PCR system that enables the simultaneous detection of HBV, HCV, and HIV with improved sensitivity and throughput using cobas 6800 and 8800 instruments.
