Sentence examples for multiplex risk from inspiring English sources

Many of these factors are components of the metabolic syndrome, a multiplex risk factor for cardiovascular disease (CVD).

Metabolic syndrome (MetS), an emerging public health problem, is multiplex metabolic risk factors associated with a 5-fold risk of T2DM and a 2-fold risk of CVDs.

The presence of more than one primer pair in the multiplex PCR increases risk for primer-dimers.

We analyzed 1,532 families from the Autism Genetic Resource Exchange (AGRE) to assess the impact of de novo and rare CNVs on ASD risk in multiplex families.

A major risk in the multiplex arrays is the increased cross-reactivity, due to the presence of multiple antibodies, which are normally applied as a mixture.

Three pairs of primer sequences displayed some degree of similarity and should be avoided as potential multiplex combinations to prevent the risk of forming primer dimers (CAM-02R CAM-15R CAM-02R CAM-15R CAM-02R CAM-15RM-06R).

This low level tiling, although efficient in terms of reducing the complexity of the multiplex primer pools, increases the risk that specific amplicons will fail to amplify due to an unknown variant (e.g. rare or private germline variants) beneath the footprint of one of the primers.

Our observation of the absence of a major increased frequency of the risk allele in multiplex ASP families when compared with sporadic cases, as reported by Begovich and colleagues [ 12], allows us to estimate the excess of allele sharing expected in the ASP analysis over the Mendel expectation of 50%.

Accordingly, multiplex-positive UA patients who are anti-CCP-2-positive have a higher risk to progress than multiplex-positive anti-CCP-2-negative UA patients (71%% versus 30%%, Fig.  4a).

Young patients had higher risks than the older ones, and multiplex families (parent and sibling proband) showed higher risks than siblings or offspring of affected parents.

Indeed, serological EBV markers are potentially useful for screening individuals with a high risk of NPC in multiplex families [ 38].