DNA fragments reveal, upon agarose gel electrophoresis, a distinctive ladder pattern consisting of multiples of an approximately 180 base pairs subunit.
Results for minimization of 20 such arrays, with different sequences and starting conformations, suggest that there are a large number of multiple minima of approximately equal energy.
In previous experiments, we observed that TTP expressed in HEK293 cells appears on SDS gels as multiple bands of approximately Mr 47,000, which collapses with phosphatase treatment to its predicted size of Mr 34,000 [26], [27], [28], [35].
They are biochemically complex structures, which contain multiple copies of approximately 30 core subunits, in turn contributing to recruit many additional regulatory proteins.
Using primers complementary to sequences in the pro/pol genes of HRV-5, multiple bands of approximately 200, 300, 700, and 1,000 bp were obtained with cartilage tissue and culture-expanded chondrocytes from all OA specimens (n = 17).
Pe'er et al. [3] estimate a multiple testing burden of approximately one million tests for genome-wide association analyses in European samples.
We synthesized several dsRNAs in E. coli that lacked the double-strand-specific RNaseIII, using a plasmid vector that harboured two T7 promoters in inverted orientations flanking either a fragment of each gene of interest, or a multiple cloning site of approximately 200 bp with no insertion [9].
Our previous work with the human pathogenic fungus Cryptococcocus neoformans [24] as well as this study showed that fungal melanin is concentrated in the cell wall and assembled into multiple concentric layers of approximately 100 nm in thickness consisting of closely packed smaller particles [25].
The Rhox4 probe hybridises to multiple HindIII fragments of approximately 20, 13, 10 and 5 kb with Asp718 producing 23, 18, 13, 10, and 8 kb fragments that are consistent with the predicted sizes from the database sequence.
